Breakthrough project officer jobs

Location:  Hybrid working - Part London office-based and part home working. The post holder will work a minimum of one day a week in the office. 

Salary: £35,225 per annum 

Hours: 35 hours per week 

Closing date: Tuesday 28 October 202510.00am 

Interview date: Tuesday 4 November on Teams. Please note that there may be a second stage in person on Friday 7 November.

This is a permanent role. 

Please note that we reserve the right to hold interviews earlier so please apply as soon as possible. 

Who we are looking for 

We are looking for an enthusiastic and highly organised individual to join our growing Individual Giving Team as a Senior Individual Giving Officer. You will work on creating our Individual Giving appeals, writing compelling communications which will inspire and drive income. You should have experience of working in a charity environment, and be able to manage multiple projects simultaneously to tight deadlines and budgets.

Experience required 

You’ll have previous experience of: 

• Managing direct marketing campaigns in a charity environment.

• Leading projects from start to finish within given budgets and timescales.

• Creating compelling and professional communications for a variety of audiences and channels. 

• Analysing campaign results and using insight to optimise future campaigns.

• Collaborative working with multiple internal and external partners to deliver campaigns. 

About Breakthrough T1D 

Breakthrough T1D is the world’s leading charitable research funder into type 1 diabetes, improving lives until we find the cure. We are dedicated to our 400,000 strong type 1 community in the UK and work closely with our international affiliates across the world, including the US, Canada and Australia. 

You will find a vibrant atmosphere and spirited team at Breakthrough T1D, always striving to make a difference to people living with type 1. 

Employee benefits 

As an employer we offer: 

• Hybrid working arrangements 

• Flexible working and will consider compressed hours 

• Generous annual leave entitlement – 25 days per year plus bank holidays for full-time staff with leave increasing after three and five years’ service 

• Health cash plan that allows you to claim for some treatments such as dental, optical and physiotherapy treatment 

• Season ticket and cycle loan 

• Pension scheme 

• Family-friendly policies – maternity, paternity, adoption and shared parental leave at enhanced rates 

• Personalised training to suit your career aspirations and professional development 

Breakthrough T1D is an equal opportunity employer, we welcome applications from all individuals regardless of race, gender, disability, religious belief, sexual orientation or age. 

Be part of the breakthrough. Help change lives through world-class medical research.

At the Medical Research Foundation, we don’t just fund research – we fuel progress. We back bold ideas, support brilliant minds, and invest in science that’s often overlooked but urgently needed.  As our remit is as broad as medical research itself, we fund an exciting variety of science and are able to step in where others cannot. We are looking for a dynamic, forward-thinking Head of Research Funding to join us on a one-year maternity cover.  This is a unique opportunity for someone passionate about improving human health and advancing medical research to step up or across into a leadership role to manage our dynamic Research Funding Team and deliver our strategic research objectives.

Why this role matters

As the Head of Research Funding, you will be the driving force of the Research Funding team, ensuring our funding mechanisms uphold the highest standards of integrity, supporting research with the greatest potential for impact.  Your leadership will be crucial in identifying new funding opportunities, maintaining rigorous oversight of grant management, and ensuring that our research funding remains innovative and effective.

You will:

•  Oversee the planning and execution of all research funding competitions and ensure the robust management of the full lifecycle of grant funding.
•  Undertake health and research landscape reviews to identify emerging areas of research need and innovation.
•  Manage and develop a team of six people, maintaining the highest professional standards.

About You

You are inspired to help us to deliver our vision of a world where medical research improves the health of everyone. 

You bring:

• A PhD in biomedical sciences or related fields; or equivalent experience and a degree in biological sciences.
• Significant experience of biomedical research funding, including developing and managing funding calls; financial oversight of funding; peer review processes; and grant management.
• Line management expertise.

Bonus points if you have:

• Postdoctoral research experience
• Experience of preparing landscape reviews and strategic cases for support.

What we offer:

• A chance to be part of a mission that matters.
• A supportive, collaborative, and ambitious team culture.
• Opportunities to grow, learn, and make a real impact.

About the Medical Research Foundation

Our vision? A world where medical research improves health for everyone. We fund life-changing science, and we’re proud of the role good governance plays in that mission.

Salary & Working Style

• £61,000 - £65,000 per year full-time (36 hours per week) dependent on experience
• 30 days' holiday plus bank holidays
• 12% employer pension contribution + life assurance
• Generous other benefits
• Wellbeing support and flexible working culture

This is a full-time post, but we are happy to consider a part-time contract (min 0.8 FTE).  This is a fixed-term maternity cover post expected to start in January 2026 and end on 31 December 2026.  We are very happy to consider secondment opportunities from other organisations.

We value spending time working in-person to develop strong connections with each other and with our mission, so you will be based at our central London office for a minimum of three days a week if you are full-time (Monday, Tuesday, and either Wednesday or Thursday) with the option to work remotely for the remainder.  If you are part-time, you will be office-based for at least 50% of your time.

A Place for Everyone

At the Medical Research Foundation, we believe that diversity drives creativity and innovation. We are dedicated to promoting equality of opportunity, fostering fairness and inclusion, and creating an environment where everyone feels that they belong.

We especially welcome applications from individuals from minoritised groups, including those from Black, Asian, and minority ethnic backgrounds, disabled people, and members of the LGBTQI+ community.

About Topos Research UK and Topos Institute

Topos Research UK is an entrepreneurial, dynamic charity start-up in the UK (inc. 2024) with a parent charity start-up, Topos Institute in the US (inc. 2019). We are a non-profit research institute dedicated to realising a world where the systems that surround us benefit us all, so that society can better cooperate on critical issues — the climate crisis, pandemic responses, agricultural modelling, global access to education, and more — through interconnected systems that consider holistic impacts. We develop new tools for collective inquiry and modelling, enabled by a combination of novel foundational mathematics, open-source software engineering, and meaningful collaboration with domain specialists.

The Opportunity

We seek a strategic Operations Director to lead the successful scaling of our rapidly growing UK operation. This is a pivotal, creative leadership role reporting directly to our Board of Trustees, with day-to-day collaboration with board representative Brendan Fong (Topos UK Trustee and Topos USA CEO).

Current State:

• 1-year-old entity with £500k annual revenue
• 6 talented staff (research scientists, software engineers, postdocs)
• 3 planned new staff members within the next 6 months
• Two major grants: £600k (1-year) and £1.2M (2.25-year)
• Projected FY26 revenue: £1M

The Challenge: You’ll be our first senior operations hire, responsible for establishing the systems and culture that will enable Topos UK (and Topos as a whole) to thrive as we scale from startup to established institution, collaborating between the UK and US offices, and pioneering a new style of technology-oriented research organisation keenly focussed on improving lives.

Key Responsibilities

Operations & Finance Leadership

• Lead operations and finance for a projected £1M+ annual budget from research grants
• Support grant solicitation, budgeting, procurement, monitoring, and reporting
• Collaborate with financial consultants on organizational strategies, budgets, treasury, and tax affairs
• Coordinate with US-based Topos Institute on governance, consolidated reporting, and shared contracts

Strategic Planning & Culture Building

• Partner with the Board of Trustees and Topos Institute USA to develop and implement strategic plans aligned with our institutional mission
• Champion the critical role of operations and administration in achieving our research mission
• Establish and nurture an organizational culture that:
  • Integrates diverse perspectives and lived experiences
  • Views uncertainty as opportunity for innovation
  • Balances operational efficiency with academic freedom
  • Embodies public purpose, intellectual rigor, and collaboration

Team Leadership & Development

• Nurture and mentor our growing team of 6+ researchers and engineers
• Support individual career aspirations while building collective capacity
• Work with HR consultants to develop talent management systems and support organizational human resources needs
• Foster an environment where exceptional people can do their best work

Systems & Infrastructure

• Design and implement policies, internal controls, and procedures for sustainable growth
• Oversee operational functions including inventory management and facilities
• Oversee compliance, risk management, and organizational governance
• Manage physical space requirements, including future lease negotiations
• Coordinate legal affairs with Board of Trustees, sourcing expertise as needed

Stakeholder Management

• Serve as operational interface with funders, partners, and collaborators
• Represent Topos UK’s capabilities and needs to external stakeholders
• Support business development for future grant and contract opportunities
• Assume additional responsibilities as organizational needs evolve

What We’re Looking For

Essential Experience

• 5+ years in senior operations/finance roles at mission-driven organizations
• Proven ability to build systems and culture from the ground up
• Experience with research institutions, nonprofits, or technology startups
• Track record managing complex budgets and grant funding
• Track record of successfully impacting both strategic and tactical finance and administration initiatives

Leadership Qualities

• Collaborative, supportive management style with focus on team development
• Skilled at building consensus in a complex organisation and able to achieve results through influence and partnership
• Ability to foster inclusive environments where diverse perspectives thrive
• Experience mediating differences and supporting individual team member success
• Ability to communicate clearly and collaboratively, both internally and externally
• Creative problem-solving approach with strong analytical skills

Cultural Fit

• Intellectually curious with appreciation for technical research
• Mission-first orientation with commitment to public benefit
• Comfortable with complexity, ambiguity, and rapid change; sees challenges as opportunities for growth
• Committed to building inclusive, supportive team environments
• Values-driven leader who can balance efficiency with academic freedom
• Motivated by meaningful work that contributes to helping solve global-scale challenges
• Values continuous learning, diverse perspectives, and collaborative problem-solving
• Ability to periodically travel to the head office in Berkeley, California, or other locations as needed
• Flexibility with working hours, to accommodate for collaboration across global time zones
• Energetic, flexible, collaborative, and proactive; a team leader who can positively and productively impact both strategic and tactical finance and administration initiatives

Preferred Qualifications

• Advanced degree in relevant field (business, nonprofit management, etc.)
• Experience with international organizations or multi-entity coordination
• Familiarity with academic research environments
• Technical literacy sufficient to engage with mathematical/computational work

Why Topos UK

Exceptional Team: Collaborate with world-leading researchers and high calibre funding agencies.

Inclusive Environment: Be part of building a diverse team where different perspectives are valued and everyone can contribute their best work.

Meaningful Impact: Your operational excellence directly enables breakthrough research on humanity’s most pressing challenges—from climate change to public health to collaborative open science.

Technical Innovation: Support the development of genuinely novel technologies that could transform how humanity approaches complex, collaborative decision-making.

Supportive Culture: Join a caring, inquiry-driven community that values both intellectual rigor and personal well-being, with a strong focus on in-person office culture but flexibility to support work-life balance.

Growth Opportunity: Shape the foundational systems of an organization poised for significant expansion and impact.

Apply

Topos Research UK is committed to equality, diversity, and inclusion. There is evidence to suggest that women and people of color are less likely to apply for jobs unless they believe they meet every one of the qualifications as described in the job description. No matter who you are, if this role speaks to you, we encourage you to apply, even if you don’t believe you tick all the boxes. We’d especially like to encourage people from underrepresented backgrounds to apply.

If you require any adjustments to the application process, such as accessibility accommodations, additional preparation time, or other, please let us know in your application. We’re happy to support your needs and adjust the application process.

Next Steps: This role offers the rare opportunity to be the operational backbone behind important research that contributes to how humanity tackles global challenges. If you’re energized by building meaningful institutions and enabling exceptional people to do transformative work, we’d love to hear from you.

Applications will be reviewed on a rolling basis. We expect the process to include initial screening, work assessments, team interviews, and references.

At Action for ME, we believe that change won't just happen; it has to be made. That's why action and impact are at the heart of everything we do. Whether that's helping people today with support, information, or care. Or working towards securing future change through our research and campaigning work.

The intent of everything we do is to pursue positive impact for the lives, rights, and futures of people affected by ME.

More information can be found in the application pack. 

You will play a pivotal role supporting the Charity in several different ways. Working with the Senior Leadership Team, you will ensure the smooth running of the organisation, providing administrative support to the Director of Operations and the Chief Executive. As a self-starter you will manage a range of tasks such as diary management, meeting minutes, assisting with event administration and HR administration. No two days will be the same!

You will be the point of contact for our HR, recruitment and training systems, ensuring consistency and assurance across the organisation. You will support HR administration such as supporting recruitment, on-boarding and off-boarding of colleagues as well as taking minutes for Board meetings, so you will need to be able to maintain a high level of confidentiality.

As a team player, you will provide comprehensive, confidential and sensitive people-orientated administration support, developing a deep understanding of our organisation, our work and build strong, effective working relationships with colleagues.

Remote working at home can be challenging for some and for others, it works incredibly well. You will need to be able to work on your own, use your own initiative and ensure you are proactive in maintain good levels of communication and contact with your colleagues to ensure we deliver the best service possible to people with ME. 

Crisis is the national charity for homeless people. We know that homelessness is not inevitable. We know that together we can end it.

Crisis is the national charity for people experiencing homelessness. We have embarked on our 10-year strategy for ending homelessness. We know it is not inevitable. We know together we can end it.

Contract: Fixed term contract or external secondment opportunity until 31 March 2026, with the possibility of extension

About the role

CTI is part of a housing-led response to ending homelessness. CTI is an evidence-based model, designed for times of transition for people who require support to navigate often fragmented systems. It uses a time limited case management approach to support people through a period of transition which works towards preventing and ending homelessness.

The model is strictly time limited and prescriptive in its application and Crisis’ CTI pilot will run close to the CTI principles. The timing of movement through the phases is defined by the Programme model.

CTI consists of four main phases:

1. Pre CTI: in which the relationship with the client is developed and their goals and ambitions are identified, (no timescale – could be days, months or years)
2. Transition: providing support & beginning to connect client to people and agencies that will assume the primary role of support and enable them to meet their goals (3 months)
3. Try out: monitoring and strengthening support network and client’s skills (3 months)
4. Transfer of care: terminating CTI and stepping right back (3 months)

The post holder will be working within the framework of CTI, supporting prison leavers from prison into accommodation, thus preventing homelessness on release from custody.

About you

To be successful in this role you will have experience of delivering person centred support with statutory and non-statutory services within the criminal justice system, offering coaching and mentoring, learning support and/or personal development training, ideally working to matrix standards. You will also have an appreciation of delivering this within a time limited framework.

You will demonstrate knowledge of issues affecting homeless or vulnerably housed individuals which could include mental illness, addiction, the benefit system and housing. Being committed to empowering homeless and vulnerably housed individuals is essential to this role.

Due to the nature of the role, it is essential that you have a valid driving licence and access to your own vehicle.

Please see the full Job Pack linked below, for a full list of requirements for this role. We realise that long lists of criteria can be daunting, and you may not want to apply for a role unless you feel 100% qualified. However, if you feel you have relevant examples to answer the screening questions, we encourage you to apply.

We believe diversity is a strength, and our aim is to make sure that Crisis truly reflects the communities we serve. We are actively working towards our organisation being a place where everyone can thrive and make their best contribution to our mission of ending homelessness for good. We know that the more perspectives, voices, and experiences we can bring to this work, the better. We particularly welcome applications from people who have lived experience of homelessness, and people from all marginalised groups, communities, and backgrounds.

Working at Crisis

Our values, Bold, Impactful, Collaborative and Equitable, are at the heart of everything we do as we continue in our mission to end homelessness.

Our staff, members and volunteers are vital to getting the right government policies in place, providing breakthrough services, and building a supportive community. We’ll lead by example to nurture a positive and ambitious workplace guided by ending homelessness.

As a member of the team, you will have access to a wide range of employee benefits including:

• A competitive salary. Please note our salaries are fixed to counter inequity and we do not negotiate at offer stage.
• Interest free loans for travel season ticket, cycle to work, and deposit to secure a tenancy.
• Pension scheme with an employer contribution of 8.5%
• 28 days’ annual leave (pro rata) which increases with service to 31 days and the option to purchase up to 10 additional days leave.
• Enhanced maternity, paternity, shared parental, and adoption pay.
• Wellbeing Leave to be used flexibly
• And more! (Full list of benefits available on website)

Alongside our excellent staff benefits, we will support your ongoing development to build your skills, experience, and career.

When you join us, you will have the opportunity to join our staff diversity networks, which aim to champion issues across the organisation, enable staff to be their authentic and best selves and contribute to making Crisis a truly diverse organisation.

How do I apply?

Please click on the 'Apply for Job' button below. Our shortlisting process is anonymised as part of our commitment to equality, diversity, and inclusion. We do not ask for CVs, instead we ask you complete the work history section and answer the screening questions for us to be able to assess you fairly and objectively. At least two members of staff score all applications.

Closing date: Sunday 26 October 23:55

Interviews will take place w/c 3 November at Crisis Skylight Merseyside, 96 Kent St, Liverpool L1 5BD

AI in Job Applications

We understand some candidates use AI tools when applying. Whilst we welcome the use of technology to support clear communication and structure, we want to learn more about you, so please ensure that your application reflects your own skills, knowledge and experiences

Accessibility

We want our recruitment process to be as accessible as possible. If you need us to make an adjustment or provide additional support as you apply for a role, please email our Talent Acquisition team will contact you to discuss how we can help.

Community Fundraiser - Home Counties

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Are you ready to take on a new challenge with a leading charity making a real difference in brain tumour research? ​

Brain Tumour Research is seeking an experienced and motivated fundraiser to join our team. As a key part of our fundraising efforts in our high-performing East region, you will have the opportunity to drive income generation through a variety of initiatives, including challenge events, fundraising groups, and corporate partnerships such as charity of the year. You will also be responsible for driving initiatives to increase our profile and supporter base within Buckinghamshire, Bedfordshire, Hertfordshire, Northamptonshire and Essex. 

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Key Responsibilities: ​

• ​Generate income across a range of community fundraising initiatives and events, with the opportunity to lead on key projects 
• Steward supporters to help drive the charity’s fundraising activities and growth 
• ​Work with the fundraising team to develop and maintain strong relationships with fundraisers, donors, partners, and key stakeholders ​
• Contribute towards the growth and success of fundraising efforts, ensuring a sustainable income stream for the vital ongoing funding of brain tumour research ​

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Requirements: ​​

• At least one year of fundraising experience, with a proven track record in income generation 
• Strong experience in supporter stewardship  
• Excellent communication skills, with the ability to engage and inspire supporters and partners alike ​
• Passion for Brain Tumour Research and its mission to fund research and ultimately find a cure 

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If you are looking for a fulfilling and impactful role and have the level of experience and skill we are looking for, we welcome your application.

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​We will give preference to those candidates living in the Bucks, Beds and Northants areas of this region.​​​

​We reserve the right to close the application window early and advise candidates to apply in good time to avoid disappointment.​

We are asking for a CV as the first step but applicants may be asked to provide a targeted covering letter as part of the selection process.  Interviews will be conducted during the application window as appropriate, and will consist of a first interview via MS Teams, progressing, if successful to a face to face second interview, held at our offices in Milton Keynes.

Closing Date: 06th November 2025

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We are looking for people who share our passion for finding a cure for brain tumours and who have the skills and experience to make a difference. We welcome applications from candidates of all backgrounds, cultures, genders, sexual orientations, abilities, and ages. We believe that diversity enriches our organisation and helps us achieve our mission. We are committed to providing an inclusive and supportive environment where everyone can be themselves and contribute to our vision.

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Operations Assistant (Full Time – Office Based)  

Job Purpose:
The Operations Assistant provides support to the HR and Operations Manager by taking day to day responsibility, under guidance, for various facilities, safety and administrative processes, including HR administration, as well as responsiblity for locking/unlocking of meeting rooms, routine health and safety tasks and other matters that contribute to making the office a pleasant and functional environment in which to work. 

The duties will also include giving regular support to the Fulfilment Manager and under their guidance, process orders and support with despatch and deliveries, in addition to providing holiday cover, when the Fulfilment Manager is away.

Many aspects of this role require Manual Handling.

The ideal candidate will have a positive ‘can do’ attitude, a personable manner, and will embrace the desire to make a measurable difference.

Brain Tumour Research is an exciting, innovative, and ambitious charity. We are passionate about finding a cure for brain tumours through the establishment of dedicated Brain Tumour Research Centres of Excellence around the UK. 

Reports to:  HR and Operations Manager 

Direct Reports: No direct reports 

Location:  Head Office, Milton Keynes (This is not a Hybrid role, and will require attendance at the office Monday through Friday – 9-5pm or 8.30 - 4.30pm) 

Requisite Skills and Experience: 

Essential: 

• Excellent administration skills, detail orientated and systematic with the ability to prioritise competing demands

• Excellent communications skills, both written and verbal with the ability to adapt communication styles to the situation and audience 

• Strong interpersonal skills, ability to work within a close-knit team and have an adaptable and can-do attitude to work 

• Experience of handling and managing confidential data 

• Ability to handle difficult and sensitive issues, and to interact with empathy, compassion, tact, diplomacy and patience 

• IT skills including detailed knowledge of using Microsoft Word and Microsoft Outlook

• Effective organisational, planning and prioritisation skills 

• To be able to assist with manual activities of a physical nature 

• Able to work independently and as part of a team 

Desirable: 

• Experience of working in the charity sector 

• Experience of HR administration 

• Experience of using HR database, such as PeopleHR 

• Experience of PeopleHR, report running 

• Knowledge of Shopify

• Experience with working with databses and phone interactions

• Manual Handling experience 

• Health and Safety knowledge 

• Experience of Facilities and the management of maintenance requests 

Main duties:  

• Update internal HR databases, such as PeopleHR and employee files 

• Managing the WorkforUs mailbox 

• Recording and running reports from the database on sickness, leave, maternity etc 

• Assist in the preparation of HR standard template documents 

• Administering the onboarding and offboarding requirements for the organisation 

• To maintain the ATS when recruitment is live, and to support with the day-to-day recruitment activity, including but not limited to liaising with candidates, setting up interviews and preparing interview packs 

• Assisting with managing and maintaining database information for employee benefit schemes 

• Maintain and Update employee notice boards for HR and H&S 

• Opening, logging and distributing inbound post 

• Support with answering phone calls into the Office and responding to general enquiries 

• Recording and reporting on Environmental data 

• Assist with co-ordinating maintenance activities for the Office space 

• Support with H&S administration, such as Risk Assessments and Accident Reporting 

• To complete basic H&S checks including walk arounds, first aid kit maintenance 

• Support with Training requirements, booking of courses and the maintenance of a skills matrix 

• Monitor and maintain stationery requirements and office supplies such as milk, water 

• To assist with the setting up and presentation of the Meeting Rooms, to keep them well presented and to ensure that they are unlocked and locked each day. 

• To support the Fulfilment Manager on a regular basis with processing orders and deliveries 

• To cover in the absence of the Fulfilment Manager, the processing of orders and deliveries

• Participate with and support the HR & Operations Manager in HR projects on an adhoc basis 

• Ensure that relevant charity and other legislation is complied with

• To comply with Brain Tumour Research’s internal policies and procedures 

• To undertake any other reasonable duties as required by the HR and Operations Manager and Director of Finance and Ops 

We reserve the right to close the application window early and advise candidates to apply in good time to avoid disappointment.

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We are asking for a CV as the first step but applicants may be asked to provide a targeted covering letter as part of the selection process.  Interviews will be conducted during the application window as appropriate, and will consist of a first interview via MS Teams, progressing, if successful to a face to face second interview, held at our offices in Milton Keynes.

Closing Date: 07th November 2025

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We are looking for people who share our passion for finding a cure for brain tumours and who have the skills and experience to make a difference. We welcome applications from candidates of all backgrounds, cultures, genders, sexual orientations, abilities, and ages. We believe that diversity enriches our organisation and helps us achieve our mission. We are committed to providing an inclusive and supportive environment where everyone can be themselves and contribute to our vision.

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