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Clinical Research Manager
The Clinical Research Manager will play a key role in advancing ARUK’s drug prioritisation activities as part of the Clinical Accelerator Programme. Working closely with the Senior Clinical Research Manager, this role will drive the identification, evaluation, and progression of high-potential drug candidates toward clinical trials, delivering tangible impact for people affected by dementia.
This role is vital in advancing Alzheimer’s Research UK’s research objectives and organisational strategy and will be key to delivering impact for people affected by dementia. The Clinical Research Manager will manage the planning and delivery of ARUK’s drug prioritisation activities working collaboratively with external stakeholders and various departments across the organisation, including the wider Research, Fundraising and Policy, Communications and Involvement Teams to develop the programme and ensure successful delivery and measurable impact.
This role sits within the Clinical Research team in the Research Directorate, an ambitious, proactive and growing team that is driving forward initiatives to bring more clinical trials to the UK for people living with or likely to develop dementia. With the first generation of disease modifying treatments recently approved, this is an exceptional opportunity for an individual with strong research experience who understands the clinical research environment in the UK, to contribute to groundbreaking work in dementia research, aligning with and advancing on the Government's new investment initiatives in the Dame Barbara Windsor Dementia Goals.
Key Responsibilities:
1. ARUK Drug Prioritisation Programme Delivery and Development
· Lead on the identification of therapies with the potential to be prioritised for clinical trials in Alzheimer’s and other types of dementia through literature search and communication with the clinical research community and key external partners, with support from the Senior Clinical Research Manager.
· Lead the development and drafting of high-quality scientific dossiers that directly inform prioritisation decisions and progression of drug candidates.
· Lead the translation of recommendations from external advisory panels into actionable next steps.
· Work with the Senior Clinical Research Manager and the Senior Clinical Programmes Operations Officer to plan drug prioritisation activities, including meeting logistics, panel engagement, feedback and to track and evaluate progress.
· Identify, evaluate, and drive forward high-impact opportunities for drug prioritisation and clinical development in consultation with Partnerships, Evidence and Funding teams.
· Design and embed scalable processes to proactively monitor the global drug development landscape, utilising databases, conference intelligence, and literature to curate a dynamic intelligence log that tracks therapeutic candidates, development progress, and emerging opportunities across industry and academia.
2. Driving the advancement of the Clinical Accelerator Programme and delivery of key components of its strategy
· Drive planning and implementation of new activities as relevant to continually develop and advance the clinical research strategy
· Collaborate in mapping the clinical research ecosystem, identifying gaps in research and recommending actions to address them.
· Keep abreast of developments and trends in dementia clinical research to influence ARUK's strategies and decisions.
· Support and continuously strengthen internal reporting mechanisms, ensuring timely, high-quality updates to Senior Leadership and relevant boards that enable effective governance, informed decision-making, and strong organisational coordination
· Work closely with the Research Involvement Manager to integrate best practices in involvement and co-production to ensure our research is relevant for and supported by people affected by dementia
· Ensure effective information-sharing across internal stakeholders, including Research, Fundraising, Finance, Policy, Communications and Involvement teams, to maximise the visibility, uptake and strategic use of Clinical Accelerator Programme outputs.
· Aid in the planning, production, and communication of clinical research-related content with the ARUK Communications and Fundraising teams.
3. Strengthening Relationships with External Stakeholders
· Foster and nurture relationships with clinical leaders and research funders in the UK to build the profile of ARUK’s clinical research and help us to accelerate research towards a cure.
· Work closely with our Research Partnerships manager to maintain and build partnerships that further our clinical research objectives.
· Support the Senior Clinical Research Manager and Head of Clinical Research in enhancing ARUK’s external profile through active participation in meetings and collaborations with key stakeholders.
Knowledge, skills and experience needed:
· PhD in a relevant biomedical field or equivalent experience in clinical or scientific research
· Strong ability to critically interpret and evaluate pre-clinical and clinical data
· Familiarity with the drug development process of taking a therapy from pre-clinical studies to regulatory approval.
· Excellent stakeholder management skills.
· Demonstrable commitment to collaborative and inclusive working.
· Proven experience in project management with the ability to adhere to deadlines and prioritise tasks.
· Understanding of research programme management.
· Experience or understanding of preparing scientific dossiers or evidence summaries to inform research prioritisation, funding, or strategic decision-making.
· Understanding of dementia research and funding landscapes.
· Experience working with biotech and pharmaceutical companies
· Exceptional scientific communication skills (written and verbal).
· Detail oriented
· Good IT skills.
· Commitment to ARUK’s vision, mission and values.
· Values the involvement of people with lived experience in research.
· Highly self-motivated with the ability to work across different teams and departments.
· Solution-focussed with the ability to problem solve creatively.
· Able to work independently.
· Collaborative approach with ability to build strong relationships with a range of stakeholders.
· Good communicator with the ability to tailor communications to a range of audiences.
Additional Information:
Ways of working:
As part of our Agile ways of working you will be required to work approximately 2 days a week from the office, which is subject to the requirements of the role and the business needs. Flexibility on where you work can be split between working from home and our office.
Roles that are classed as part of the Agile ways of working are not able to claim any costs for Mileage/Travel on Public Transport, Accommodation and/or Meals. This includes when attending the office for various meetings/events.
Our Office: Our office is at 3 Riverside, Granta Park, Great Abington, Cambridge, CB21 6AD.
Salary: Circa £46,000 per annum, plus benefits.
Please download the Vacancy Pack on our website for more information.
The closing date for applications is the 28th June 2026, with interviews being arrange once shortlisting has been completed. Please indicate in your covering letter if you are unable to attend an interview on a certain date. We would encourage you to submit your application at the earliest opportunity, as on occasion we may have to bring forward the interview date and/or the closing date based on the needs of the business. Although a possibility, this will only happen in exceptional circumstances. Please indicate in your covering letter if you are unable to attend an interview on a certain date.
We value diversity and are committed to creating an inclusive culture where everyone can be themselves and reach their full potential. We actively encourage applications from people of all backgrounds and cultures, particularly from those in the global majority, those with disabilities, men and those from the LGBTQIA+ community. Any offer of employment is however subject to you having the right to work in the UK.
As part of our commitment to being an inclusive employer and ensuring fairness and consistency in our selection process, we will handle your CV and application with the utmost confidentiality. Should you require any adjustments at either the application or interview stage, please contact us at via our website.
How to apply: Please create an online account using our Online Recruitment Platform which can be accessed through our Job Vacancies page. You will be able to attach your CV to your application and track the status of your application.
About Alzheimer’s Research UK: Alzheimer's Research UK is the UK's leading dementia research charity. Our mission is to accelerate progress towards a cure. Today 1 in 2 people will be impacted by dementia, either through caring for a loved one, developing it themselves or tragically both. But there is hope.
The client requests no contact from agencies or media sales.
Lead Software Engineer - FTC
As the UK’s leading dementia research charity, we’re determined to stop this from becoming a reality. We’re working to revolutionise the way we treat, diagnose and prevent dementia. But we will not stop there. With your support, we will keep going until every person is free from the heartbreak of dementia. We exist for a cure. In order to make this happen, we need to operate with best in class Digital and Technology tools and platforms.
So, join us as we embark on a major journey of transformation across our digital, data, and technology offering! The Lead Software Engineer will play a critical, hands-on role in shaping this future.
We are investing in a new website platform that will provide an improved user experience, be built and operated using modern Tech (e.g. React, headless CMS, CI/CD) and be a foundation for continued future optimisation. The website will unlock the ability to attract more users (via increased visibility on search engines and repeat visits) and increase the number of people donating online for a cure.
This role will be the senior technology team member on the new website project team, ensuring that the solution designed and delivered primarily by our website development partner is using modern approaches and tools. In addition, this person will actively take part in the development and test of the website platform and ultimately be the internal technical owner of the platform for ARUK.
The post holder will report into the CIO but work day to day with the Digital Engagement team to deliver the new website platform.
This is a 24-month fixed term contract.
Key Responsibilities:
· Act as the internal technical owner of the new website platform, providing strong technical leadership, governance, and assurance across its design, build, and operation.
· Provide technical oversight and direction to the appointed Digital / website development partner, ensuring best practice engineering approaches, tooling, and standards are applied throughout delivery.
· Own and make key technical design decisions, ensuring the website platform:
o Uses modern web and cloud‑native technologies (e.g. React, headless architecture).
o Uses modern technical approaches for code management, build and deployment pipelines (CI/CD).
o Aligns with Alzheimer’s Research UK’s broader enterprise architecture, security standards, and technology roadmap.
o Integrates effectively with existing and future Alzheimer’s Research UK’s systems (e.g. CRM, fundraising, analytics, marketing platforms).
· Actively contribute as a hands‑on software engineering individual contributor during the build and test phases, including:
o Reviewing and contributing to code where appropriate.
o Supporting technical problem‑solving and performance optimisation.
o Participating in testing, release, and deployment activities.
· Work closely day‑to‑day with the Digital Engagement team, ensuring technical delivery supports user experience, content, fundraising, and optimisation objectives.
· Establish and embed good engineering practices for the platform, including documentation, environment management, deployment, monitoring, and support handover.
· Take technical ownership of the platform post‑launch, supporting continuous improvement, optimisation, and future enhancements.
Knowledge, skills and experience needed:
· Strong professional experience as a senior software engineer / lead software engineer working on modern website or digital platforms.
· Ideally a full stack engineer with strong front-end skills (our main languages/ frameworks are React and Python/Django).
· Proven experience with modern front‑end and web architectures, including:
o React (or comparable modern JavaScript frameworks).
o Headless CMS and API‑driven architectures.
o CI/CD pipelines and automated testing practices.
· Experience acting as a technical owner or lead for an app or website.
· Experience working with modern code management tools e.g. github, bitbucket) and of version control/code branching approaches.
· Experience using AI tools to improve engineering efficiency e.g. Cursor, Claude code, github copilot.
· Knowledge of code build and deployment processes
· Solid understanding of cloud‑hosted, scalable, and secure web platforms, including performance, resilience, and security considerations.
· Experience integrating websites with wider digital ecosystems (e.g. CRM, analytics, marketing automation, donation/payment platforms).
· Ability to operate effectively as both a hands‑on contributor and a senior technical advisor, balancing strategic oversight with practical delivery.
· Experience working in an agile environment using development workflow tools such as JIRA.
· Strong communication skills, with the ability to explain technical concepts clearly to non‑technical stakeholders
Additional Information:
Ways of working: As part of our Agile ways of working you will be required to work approximately 2 days a week from the office, which is subject to the requirements of the role and the business needs. Flexibility on where you work can be split between working from home and our office.
Roles that are classed as part of the Agile ways of working are not able to claim any costs for Mileage/Travel on Public Transport, Accommodation and/or Meals. This includes when attending the office for various meetings/events.
Our Office: Our office is at 3 Riverside, Granta Park, Great Abington, Cambridge, CB21 6AD.
Salary: Circa £63,000 per annum, plus benefits
Please download the Vacancy Pack on our website for more information.
The closing date for applications is the 21st June 2026, with interviews being arrange once shortlisting has been completed. Please indicate in your covering letter if you are unable to attend an interview on a certain date. We would encourage you to submit your application at the earliest opportunity, as on occasion we may have to bring forward the interview date and/or the closing date based on the needs of the business. Although a possibility, this will only happen in exceptional circumstances. Please indicate in your covering letter if you are unable to attend an interview on a certain date.
We value diversity and are committed to creating an inclusive culture where everyone can be themselves and reach their full potential. We actively encourage applications from people of all backgrounds and cultures, particularly from those in the global majority, those with disabilities, men and those from the LGBTQIA+ community. Any offer of employment is however subject to you having the right to work in the UK.
As part of our commitment to being an inclusive employer and ensuring fairness and consistency in our selection process, we will handle your CV and application with the utmost confidentiality. Should you require any adjustments at either the application or interview stage, please contact us via our website.
How to apply: Please create an online account using our Online Recruitment Platform which can be accessed through our Job Vacancies page. You will be able to attach your CV to your application and track the status of your application.
About Alzheimer’s Research UK: Alzheimer's Research UK is the UK's leading dementia research charity. Our mission is to accelerate progress towards a cure. Today 1 in 2 people will be impacted by dementia, either through caring for a loved one, developing it themselves or tragically both. But there is hope.
The client requests no contact from agencies or media sales.
Job title: The Social Change Nest Financial Controller (Client Funds)
Role Purpose:
This role sits at the heart of our financial controls at the Social Change Nest and combines cash management oversight, payment operations and financial compliance. However, this is not a traditional Financial Controller position. You will work with the team to ensure robust financial controls, accurate reconciliations, secure payment processes and transparent reporting for our diverse portfolio of social impact clients. You will also be a key driver of operational improvement, identifying better ways of working as we scale.
About the Social Change Nest
The Social Change Nest (SCN) is a fiscal hosting organisation that removes the financial and administrative barriers preventing grassroots groups and informal movements from accessing funding. Since 2021, we have supported 700+ groups across the UK and internationally, helping them access over £50 million in funding for causes ranging from climate and housing to racial justice and social wellbeing. We also work closely with funders, providing Grant Distribution and Fund Management services, enabling us to support social action with confidence and transparency. We are at the forefront of fiscal hosting in the UK!
We’re a growing business operating at pace. We’ve established a lot – but as we grow, we’re still working some things out. The right person will thrive in this environment and relish building out a future-facing finance function. You’ll enjoy problem-solving, feel comfortable handling multiple priorities at once, and seek collaborative solutions. You’ll be adaptable, able to shift focus quickly when things change, and ensure strong communication across the team and with clients to keep everything aligned.
Key Responsibilities:
1. Payment Processes & Systems Management
●Own and optimise the end-to-end payment infrastructure (banking platforms, expense management tools, Open Collective platform and accounting system integrations)
●Design, implement and monitor robust internal controls to prevent fraud, errors or unauthorised disbursements
●Streamline high-volume payment workflows while maintaining strict adherence to SCN policies
2. Bank Reconciliations & Treasury
●Ensure all client bank accounts are reconciled accurately and daily
●Investigate and resolve any variances between bank statements and the internal ledger immediately
●Track client cash positions to ensure sufficient liquidity for planned social project disbursements
3. Financial Reporting & Compliance
●Produce clear, concise financial reports for clients detailing fund movements and remaining balances
●Act as the lead contact for external audits regarding client cash and payment controls. Support the preparation of year end accounts and SCN’s external Audit as it interfaces with Client funds.
●Ensure all cash management and payment processes comply with UK Anti-Money Laundering supervision and relevant HMRC requirements
4. Operational Innovation & Client Service
●Proactively research and implement new financial technologies to enhance speed, security and transparency of client services
●Continuously evaluate existing workflows to eliminate bottlenecks and improve the client experience
●Lead the roll-out of new financial tools or system upgrades, ensuring smooth transition for internal teams and external partners
5. Leadership & Collaboration
●Line manage 1–2 members of the finance team, providing mentorship and support
●Being the point of escalation for the Finance and Delivery teams on more complex finance queries and dealing directly with our clients for financial solutions
●Contribute to finance team planning and lead on delivery of key projects
●Collaborate effectively with internal and external stakeholders across the organisation
Skills and Experience:
Essential
-managing multi-currency transactions, FX impacts and global banking corridors
-oversight of restricted funds, ensuring disbursements align with specific grant conditions and reporting requirements
-implementing AML and KYC protocols and ensuring rigorous due diligence on all fund movements
Desirable
Location: London/Hybrid preferred – 2-3 days /week in the office
Reporting To: Finance Director
Contract: Full time, Permanent (flexible working considered)
Salary: £58,000-£60,000
Date Closes: Thursday 11th June
Right to Work in the UK required, no sponsorship available.
Benefits:
ABOUT US
The Economist Educational Foundation is a fast-growing charity on a mission to ensure that every child is empowered to think critically and communicate effectively about the world’s most complex current issues.
Last year, 10,800 teachers downloaded Topical Talk lessons, reaching 532,000 children in over 86 countries. We are on track to double this number, reaching over 1 million school children by the end of this academic year.
Topical Talk helps children join inspiring discussions about the news by providing:
Our programme has received international recognition, including from HundrED as one of the top 100 education initiatives, from UNESCO as a winner of the Global Media and Information Literacy Awards 2022 and from the Money And Inclusion Awards (MAIA) for best content in 2025.
THE ROLE
We are looking for a highly organised and proactive Senior Fundraising Officer to join our team on a fixed-term contract.
Working closely with the Director of Fundraising and the Senior Fundraising Lead, you will ensure our high-value corporate partnerships run smoothly, our high-net-worth events are a success and our external pitches are sharp and well-researched.
This role offers a fantastic opportunity to develop your hands-on experience across corporate, trusts and foundations and individual giving within a fast-growing charity backed by a globally recognised brand.
RESPONSIBILITIES
Research and opportunity generation
Funding applications and pitch support
Partnership coordination
Fundraising operations support
REQUIRED SKILLS, ATTRIBUTES AND EXPERIENCE
Skills and attributes
Experience
You must have:
You might have:
We’re particularly keen for you to apply if you are from a community under-represented in the charity sector or have lived experience of facing extra barriers because of your background.
We enable disadvantaged children to build essential critical-thinking and communication skills through inspiring discussions about the news.
The client requests no contact from agencies or media sales.